拷贝数改变在三阴性乳腺癌患者中经常发生。在这里，作者确定了FAD合成酶（FLAD1）在TNBC中作用的拷贝数扩增，并从机制上证明了这种扩增通过FLAD1/LSD1/SREBP1轴增加脂质代谢来驱动肿瘤发生。

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Oral contraceptive pills (OCPs) are commonly used for contraception, but their long-term effects on oxidative stress, lipid profiles, and liver function remain unclear. This study aimed to evaluate ...

Discover how a groundbreaking study links cholesterol-lowering therapy to reduced bladder cancer growth offering hope for ...