Microglia, often referred to as the nervous system’s immune cells, monitor neuronal health. They are activated by neuronal injury or infection to produce pro-inflammatory factors (M1 phenotype ...

We report that P2X7 enhances the expression of the autophagic marker microtubule-associated protein 1 light chain 3 (LC3)-II, via mTOR pathway and concomitantly with modulation of anti-inflammatory M2 ...

Microglia are key immune cells that respond to microenvironmental changes during ischemic stroke. The M1 subtype of microglia is a proinflammatory phenotype that promotes neuroinflammation-induced ...