The role of phosphorylation in regulating protein function and cellular signaling is perhaps one of the most important questions in biology. Classical methods like mobility-shift assays allow ...

Mass spectrometry–based proteomics is still ... Researchers led by Steven Gygi at Harvard Medical School compared the phosphorylation status of proteins in yeast cells with or without active ...

A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

Additionally, we employ quantitative mass spectrometry -based proteomics on assessing the protein abundance changes, as well as phosphorylation status of the tissues/cells. Furthermore, combining the ...

Aberrant phosphorylation is associated with multiple ... While it uses various instruments and approaches, mass spectrometry-based techniques are typically employed. Other techniques used in ...