Starting with 15 mg/week subcutaneous versus oral methotrexate was associated with higher clinical efficacy but more withdrawal due to toxicity in early RA. In longstanding RA, after failure on 15 ...

Side effects of biologic drugs may include: respiratory infections headaches flu-like symptoms swelling, itching, or a rash at the injection ... methotrexate, you’ll take 2.5 milligrams (mg ...

infusion over 3 h 15 Paclitaxel 135 mg/m 2 by iv. infusion over 3 h Etoposide 150 mg/m 2 iv. infusion over 1 h Methotrexate 50 mg by intramuscular injection repeated every 48 h for a total of four ...