A further understanding of the mechanisms behind OPCs' and oligodendrocytes' differential response to microglia may aid in the development of therapies for several CNS diseases where microglial ...

NG2 cells, or polydendrocytes, are a population of CNS cells that are distinct from neurons, mature oligodendrocytes, astrocytes and microglia. They can be identified by the expression of the NG2 ...

Through single-cell and lineage tracing analyses, the researchers revealed that some astrocytes could transdifferentiate into oligodendrocytes under injury-induced conditions, thereby contributing ...

To learn more about the lives of oligodendrocytes, Robert Hill, a neurobiologist at Dartmouth College and coauthor on the study, turned to cell death. While Hill and his team have studied ...