In a study, transient receptor potential canonical (TRPC) channel, a cation channel of the transient receptor potential family, was reported to have a predominant action in Müller cells and microglia ...

Methods: CTGF expression patterns were studied by immunohistochemistry in the retina of eyes of 36 diabetic persons and 18 non-diabetic controls and compared with markers of endothelial cells (CD31, ...

Discovering how the specific pathways that regulate retinal microglia and determine how these are altered during acute and chronic inflammation in Uveitis and AMD, will permit identification of ...

Müller cells were reprogrammed into photoreceptor cells to cope with the injury. However, after mutation of miR-18a in the retina, retinal microglia are activated, the expression of inflammatory genes ...

Neuroinflammation is characterized by the activation of microglia after stroke, which disrupts the cardiovascular-related neural ... Stroke is focal neurological dysfunction caused by a hemorrhage or ...

A study led by Turkish researcher Pinar Ayata unveiled a critical mechanism involving microglia—specialized immune cells in the brain—that could open new avenues for treating Alzheimer's ...

Macrophages on the surface of the retina look and act like microglia, the sentinels of the central nervous system. They had been studied extensively in rodents but haven’t been visualized in real time ...

The researchers, led by a team from the City University of New York (CUNY), believe this pathway – called the integrated stress response (ISR) – causes brain immune cells called microglia to go 'dark' ...