Delineation of how they switch between these roles is fundamental to understanding disease. Discovering how the specific pathways that regulate retinal microglia and determine how these are altered ...

Macrophages on the surface of the retina look and act like microglia, the sentinels of the central nervous system. They had been studied extensively in rodents but haven’t been visualized in real time ...

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...

Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...

Ncardia’s iPSC-derived microglia may aid ALS research and help to screen new therapies that target inflammation in ALS.

just like the macrophages in the retina adjacent to the vitreous body, the so-called microglia." Prof. Dr. Peter Wieghofer, University of Augsburg As they are not, as previously assumed ...