There are also several nuclear gene products that regulate mitochondrial gene expression 21. Amost all of these genes have been characterized at the cDNA level and several at the genomic level in ...

Mitochondrial gene products interact with those encoded in nuclear genes ... Her PhD at Duke University focused on the role of oxygen in insect body size regulation. After a postdoctoral fellowship at ...

How is mitochondrial gene expression monitored and regulated within the cell? Surprisingly, this very simple and basic question is very poorly understood in general let alone how it occurs under ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.

* Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado 80309, USA Howard Hughes Medical Institute and Department of Biochemistry, University of Texas ...

Gene editing technologies have revolutionized the field of genetics, allowing researchers to make targeted changes to the DNA of various animal and plant nuclei, animal mitochondria, plant ...

Understanding the physiological regulation and significance of selective autophagy may lead to a variety ... This multidisciplinary style avails of cutting edge strategies in molecular cell biology ...

Researchers employed a programmable DNA base editing technology to introduce a knockout mutation in the ND5 mitochondria gene, aiming to investigate the resulting genotypic and phenotypic changes.

More information: Kai Chen et al, mLumiOpto Is a Mitochondrial-Targeted Gene Therapy for Treating Cancer, Cancer Research (2024). DOI: 10.1158/0008-5472.CAN-24-0984 ...

Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.