Withdrawal symptoms from opioids can be very uncomfortable ... and opioids are synthetic. For example, morphine is a natural opiate, fentanyl is a synthetic opioid, and heroin is a semisynthetic ...

However, opioids are highly addictive drugs that can cause painful and potentially dangerous withdrawal symptoms. The withdrawal timeline ranges from days to weeks after discontinuing use.

Morphine sulfate 15mg ... buprenorphine); may reduce effects and/or precipitate withdrawal symptoms. May antagonize diuretics; monitor. Paralytic ileus may occur with anticholinergics.