The vessels in the adult mouse colon were stained by the cardiovascular perfusion of wheat germ agglutinin (WGA)-Alexa Fluor 448 and by CD31 immunoreactivity. Nerve fibers, enteric glia, and ...

In a mouse with a functioning stem cell niche, the large intestine consists of numerous villi and crypts. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases ...

Overview: The streptomycin-treated mouse is the model of choice for determining the relative fitness of enteric bacteria for intestinal colonization, which can be subdivided in two distinct stages, ...

The bioinformaticians investigated the epigenetic patterns (methylation trajectories) of the male mouse colon at different stages of aging. In addition to the continuous DNA methylation changes ...

The enriched DNA amounts were quantified with the results of IgG and the input DNA. Immunofluorescence staining of mouse colon sections was performed as previously described (26). The sections were ...

Background: Mouse models of colitis and cancer are indispensable for our understanding of the ... A novel miniendoscope (1.9 mm outer diameter), denoted Coloview, was introduced via the anus and the ...

As crypt density and colon length do not appear to increase over time, total crypt number must be regulated by a homeostatic process in which the fission-driven increase in crypt number is balanced by ...

The mice with this environmental disruption to their circadian clocks had a higher incidence of colon cancer than tumor-prone mice kept in consistent 12-hour light-dark cycles, and also had ...

These results were consistent across mouse models of colon cancer the researchers studied, along with organoids—lab-grown miniature organs—derived from human colon cancer patients. This is the ...