None of the genes previously described for familial heterotaxy were found in this interval, indicating a novel mutation in this mouse model of heterotaxy. We recently recovered several mouse ...

Next, the researchers examined the effects of the mutation in a mouse model of tauopathy. These experiments, too, suggested protective effects. The mice displayed reduced tau phosphorylation in their ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the ... regardless of the genetic mutation causing their disease.

The mouse model closely mimics the specific dysferlin mutation and resulting disease, and enabled the researchers to evaluate how the complete therapy works—taking muscle stem cells, correcting ...

In attempting to engineer a genetic mouse model for a human disorder, for example, it is important to know what kind of mutation causes the disease (for example, is the disease null, hypomorphic ...

Study results indicated that controlling diabetes with insulin helps to prevent the emergence of antibiotic-resistant S. aureus.

Mutations in this gene have been linked to ... Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders, Cell Reports (2024).

Antibiotics are powerful, fast-acting medications designed to eradicate bacterial infections. However, in recent years, their dependability has waned as antibiotic resistant bacteria continues to ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50% in a mouse model of the fatal neurodegenerative ...