dendritic cells (DCs), natural killer (NK) cells and other types of innate immune cell and humoral components, which have important inductive or effector roles to provide protective immunity 4.

A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

FBP1, a gluconeogenesis enzyme, suppresses glycolysis in NK cells, and its inhibition can recover NK cell activity, suggesting a role in NK cell exhaustion. TIPE2, a negative regulator of IL-15 ...

FBP1, a gluconeogenesis enzyme, inhibits glycolysis in NK cells and can restore NK cell function, indicating a role in NK cell exhaustion. IPE2, a negative regulator of IL-15 signaling ...

To lend the NK cells a helping hand, Carlsten’s team introduced a piece of RNA encoding fucosyltransferase 7 (FUT7), an enzyme that adds fucose to the E-selectin receptors. The researchers injected ...

Infection with hepatitis D viruses causes severe inflammation of the liver. An MHH team has now identified a marker on natural killer cells that is influenced by the anti-inflammatory effectiveness of ...

Get Instant Summarized Text (Gist) A phase 1 clinical trial indicates that a new off-the-shelf immunotherapy using CAR-NK cells shows promise for treating B-cell lymphomas. This approach, derived ...