研究数据显示，在年轻组（20-30岁）中，NK细胞的平均比例为12.5%，但在50岁以上的人群中，这一数值骤降至7.8%。更重要的是，NK细胞的功能也出现了下降：它们释放穿孔素和颗粒酶的能力减弱，对癌变细胞的杀伤效率大幅降低。

最新研究显示，NK细胞在衰老过程中扮演着免疫监测的关键角色。随着年龄的增长，NK细胞的功能障碍与感染风险增加、恶性肿瘤的发展、炎症性疾病的加剧以及衰老细胞累积的负担加重之间存在密切联系。

Unlike CAR-T cells, NK cells don’t need genetic modification to recognize a specific threat — they act broadly without ...

A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

Brain metastases are one of the most severe complications of melanoma, the most aggressive type of skin cancer. Researchers ...

Prof. MENG Guangxun's team from the Shanghai Institute of Immunity and Infection of the Chinese Academy of Sciences, and collaborators, have revealed a novel mechanism whereby a short form of IL-18, ...