Animal studies suggest that various adverse consequences of smoking are primarily due to the pharmacological actions of nicotine through acetylcholinergic nicotinic receptor activation.

Tests with receptor antagonists indicated that these drug effects are mediated by central, but not peripheral, nicotinic receptors. There was an age-related decline in self-administration of nic ...

Kineta has found a new home for deals with Genentech and Merck & Co. Tidying up the portfolio ahead of its merger with TuHURA ...

Nicotinic acetylcholine receptors play a crucial role in this process. According to Moen, when these receptors behave ...

who studies nicotinic receptors at the University of Chicago. But an epibatidine-related compound tested by Abbott Labs as an analgesic in the late 2000s caused uncontrollable vomiting, McGehee says.

Miwa’s initial work showed that lynx1 was concentrated in the nervous system. Additional studies in collaboration with Ibañez-Tallon showed that lynx-1 altered the function of nicotinic acetylcholine ...

Nicotine, a major component of tobacco smoke, could exert either nonreceptor-mediated biological effects or, more importantly, act on the different subtypes of nicotinic brain receptors ...

Brandon Henderson, Ph.D., associate professor of biomedical sciences at the Marshall University Joan C. Edwards School of ...