ukaachen.de Objectives Increasing evidence suggests that oxidative stress may play a key role in joint destruction due to rheumatoid arthritis (RA). The aim of this study was to elucidate the role of ...

This useful study partially succeeds in providing solid evidence in support of the therapeutic potential of the plant-derived compound eugenol for ameliorating symptoms associated with STZ-induced ...

We explored the therapeutic effect and underlying mechanism of PUE on cerebral I/R injury by inhibiting oxidative stress related to the PI3K/Akt/Nrf2 pathway in vitro and in vivo. Methods: The middle ...

2014; Forman and Zhang, 2021). Elevated levels of reactive oxygen species (ROS) induce oxidative stress, promoting myocardial cell death and cardiac dysfunction. As a crucial regulator of redox ...

The Chang Lab at Princeton Chemistry continues in its mission to elucidate the role of metal nutrients in human biology: last ...

Nrf2 is a ubiquitously expressed transcription factor that regulates the expression of around 20 antioxidant genes to provide protection against oxidative stress. Some of these genes are ...

Glycogen synthase kinase (GSK) 3β is an indispensable regulator of the oxidative stress response. However, the exact role of GSK3β in CHC is uncertain and was examined. Design GSK3β and Nrf2 ...

Consejo Superior de Investigaciones Científicas (IQM-CSIC), Instituto de Química Médica, 28006 Madrid, Spain ...