p53 or degrons from ornithine decarboxylase. Proteasome inhibitors and stabilizing mutations in the target increase the intensity of the EGFP signal relative to the dsRed signal. Although in-depth ...

Eflornithine irreversibly blocks ornithine decarboxylase (ODC), a key enzyme involved in cell division and proliferation associated with various types of cancer. It received orphan drug and ...