To identify novel bone remodeling factors and related mechanisms involved in both osteoclast and osteoblast differentiation, a team of researchers led by Professor Tomoki Nakashima from the ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

To identify novel bone remodeling factors and related mechanisms involved in both osteoclast and osteoblast differentiation, a team of researchers led by Professor Tomoki Nakashima from the ...

To identify novel bone remodeling factors and related mechanisms involved in both osteoclast and osteoblast differentiation, a team of researchers led by Professor Tomoki Nakashima from the ...

Bones are constantly being remodeled through the action of osteoclasts, which break down bone tissue, and osteoblasts, which create new bone tissue. Both cell types develop from immature precursor ...

In 1868, Drs. Ernst Neumann and Giulio Bizzozero first proposed that bone marrow—the soft tissue inside certain bones of the body—is where blood is made. Since then, research on bone marrow ...

The team tackled a critical challenge in treating multiple myeloma -- a blood cancer where malignant plasma cells accumulate in bone marrow ... bone-resorbing cells (osteoclasts) and enhancing ...