In addition to these decisions, which are made in the G1 phase of the cell cycle, checkpoints that operate ... but many of these signals feed into the p53 pathway.

p53 is central to the body's defense against cancer, tasked with regulating the cell cycle and triggering the death of damaged cells before they can become malignant. However, in more than 50% of ...

Cell cycle regulation, which determines the process of regular cell division, also no longer functions correctly. In addition, the so-called p53 regulation is significantly altered in these cells ...