Th17 cells have recently been suggested to play a pathogenic role in experimental autoimmune encephalomyelitis and collagen-induced arthritis (a model of rheumatoid arthritis). However ...
The balance between T helper 17 (Th17) cells and regulatory T cells ... such as interleukin-6 (IL-6), interferon-γ (IFN-γ), and granulocyte-macrophage colony-stimulating factor (GM-CSF ...
They have both pathogenic and protective functions ... Activated pDCs promote generation of both Th1/Th17 cells [46,76,87,92] and Tregs [104,105]. IFN-β treatment decreases the ability of pDCs ...
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