Standard G-binding chromosome analysis of bone marrow cells revealed a normal karyotype ... 2 courses of consolidation therapy showed the Philadelphia (Ph) chromosome in two cells out of 20 ...

Each chromosome pair viewed in a karyotype appears to have its own distinct "bar code" of bands. What changes do scientists look for in a karyotype when diagnosing diseases and disorders?

An example of a balanced structural change is the Philadelphia chromosome translocation previously described. In that case, although genetic information was rearranged into an abnormal gene ...