Mysterious Blobs Found inside Cells Are Rewriting the Story of How Life Works Tiny specks called biomolecular condensates are ...
These two types of RNA granules aggregate translationally-silenced mRNAs and function as an extension of translation regulation and are key structures that regulate the mRNA cycle. Translational ...
After UV-induced RNA damage, the proteins DHX9 (green) and G3BP1 (red) form stress granules in the cytoplasm. The cell nuclei are displayed in blue colour. DHX9 is also found in the nucleus.
Cytoplasmic RNA granules ((Stress Granules (SG) and P-bodies) function in translation regulation by sequestering translationally-silenced mRNAs but also play prominent roles in the integrated stress ...
These DPRs bind to G3BP1 far more strongly than the RNA molecules that usually activate it. This excessive binding forces G3BP1 into overdrive, triggering the formation of stress granules ...
Tyler received his Bachelor of Science in Molecular and Cellular Biology from Johns Hopkins University in 2022 where he performed research on RNA-stress granules under Dr. Tatjana Trcek. Before coming ...