Computational tool incorporates transcriptome size to improve RNA-seq analysis
Researchers studying gene expression have access to vast amounts of data from cells or tissues. This is thanks to advances in ...
eLife1 天
Single-cell sequencing provides clues about the developmental genetic basis of evolutionary ...
This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...
腾讯网14 天
直接RNA测序解锁m6A，中国科学家揭示细胞命运调控新机制
【导读】外转录组修饰，尤其是N6-甲基腺苷（m6A），是基因表达的关键调控因子，影响着RNA的稳定性、剪接和翻译等过程。从Nanopore直接RNA测序（DRS）数据中检测m6A的传统计算方法受限于对实验验证标签的依赖，往往会导致对修饰位点的低估。在 ...
腾讯网14 天
Nature Methods | 单细胞多模态测序的未来：UDA-seq如何引领新革命？
引言近年来，单细胞RNA测序技术（scRNA-seq）在揭示复杂生物系统和探索遗传学及临床研究中取得了突破性进展。然而，仅依赖单一的转录组信息往往难以区分分子相似但功能差异显著的细胞类别。因此，融合多种模态信息的单细胞测序技术逐渐成为研究热点，通过同时获取单个细胞的多维数据，研究人员能够更全面地解析细胞状态及其 ...
Computational tool extracting disease-specific drug response signatures could improve ...
A new computational tool could help researchers identify promising drug combinations for treating cancer, according to a new ...
Good immune functions could enhance cow milk quality and health
Researchers have identified various distinctive immune cells in cow's milk, creating potential avenues for enhancing animal ...
NGS-Based RNA Sequencing Market To Surpass USD 12.1 Billion By 2032, Growing At A CAGR Of 17.1%
Rising demand for precision medicine & groundbreaking innovations in RNA sequencing drive growth in oncology, drug discovery, & personalized therapies. Akash Anand SNS Insider Pvt. Ltd 415-230-0044 ...
New Food Magazine18 小时
New research uncovers molecular trigger for childhood food allergy disorder
Scientists have identified a key food allergen behind eosinophilic esophagitis, offering new hope for diagnosis and treatment ...
Akribion Therapeutics exits from stealth with €8m seed financing to pioneer RNA-guided ...
Akribion Therapeutics ("Akribion"), the early-stage biotech developing a unique, RNA-guided, nuclease-based technology for programmable cell depletion, today announces its exit from stealth and the ...