Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...
这在很大程度上受到了过去 60 多年关于 RNA 结构的错误观念的影响。王运星实验室的研究结果颠覆和更正了这些观念,并提出了用“准等能量”分子构象转换概念,来概括全新的 RNA 分子在溶液中的行为。
2025年2月4日发表在《eLife》杂志上的一项新研究可能会导致基于rna的药物开发取得突破。马里兰大学的研究人员使用微型线虫作为模型来研究dsRNA分子如何自然进入细胞并影响许多后代。研究小组发现了dsRNA进入线虫细胞的多种途径,这一发现可能有助于改善人类的药物输送方法。
Argonaute proteins contain four conserved domains: the N-terminal, PAZ (which is responsible for small RNA binding), Mid and PIWI (which confers catalytic activities) domains. Argonaute proteins ...
RNA is extremely fragile, and thus rapidly broken down if it is not protected. The study produces some of the first evidence that plants can secrete viable RNA onto the surfaces of their leaves.
Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to ...
RNA plays an important role in this inactivation process. Specifically, Xist RNA, a long noncoding RNA molecule, is responsible for crumpling up one copy of an X chromosome in each female cell.
RNA is formed by linking molecules of ribose (a monosaccharide) with phosphate groups that bind to four types of nitrogenous bases: adenine (A), guanine (G), cytosine (C) and uracil (U).
The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...