How is the same process responsible for genetic recombination and diversity also the cause of aneuploidy? Understanding the steps of meiosis is essential to learning how errors occur. Researchers ...

ATM probably also has roles in homologous recombination. ATM is a Ser/Thr kinase mutated in the cancer-prone disease ataxia telagiectasia (A-T). ATM activated by DSBs triggers cell cycle checkpoints ...

If the methylation of new DNA strands synthesized during the S phase of meiosis I in males was delayed until after recombination was initiated, the various chromatids could tell sister from non ...

In eukaryotes, genetic recombination during meiosis can lead to a novel set of genetic information that can be passed on from the parents to the offspring. Most recombination is naturally occurring.

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during ...

In Meiosis I homologous chromosomes separate, which requires pairing, synapsis, and recombination. In Meiosis II sister chromatids segregate from each other similarly to mitosis. Meiotic events must ...

Learn more Meiosis is a specialized cell division that generates gametes in every sexually reproducing organism, from fungi to humans. During meiosis in most organisms, recombination helps homologous ...

Defects in genome stability are associated with cancer, aging and birth defects such as Down syndrome. We are investigating the interplay between chromosome structure and DNA recombination during ...

In addition, triploid embryos with lower numbers of recombination, the genetic exchange that occurs during meiosis, were more ...