Damage to myelin, the protective sheath surrounding nerve fibers, impairs the brain's ability to transmit signals efficiently ...

Electron micrographs of the lumbar spinal cord showed remyelination in EAE-induced, Lingo1-knockout mice, but demyelination in wild-type control mice. Next, the authors tested whether inhibition ...

Inhibition of an ESI1 target promotes oligodendrocyte myelin production in mice, as shown as a dense curtain of green strands. This small molecule shows early promise as a potential treatment for ...