NRTI = nucleoside reverse transcriptase inhibitor, NNRTI = nonnucleoside reverse transcriptase inhibitor, PI = protease inhibitor. b While this has not been reflected in the IAS-USA and BHIVA ...

HIV-1 reverse transcriptase inhibitors are crucial components in the treatment of HIV, a virus that leads to acquired immune deficiency syndrome (AIDS). These inhibitors are categorized into two ...

Summary: While single mutations confer resistance to earlier nonnucleoside reverse transcriptase inhibitors (NNRTIs), etravirine exhibited an increased barrier to resistance by requiring multiple ...

The four main classes, which most people are treated with, target one of three viral proteins which control HIV’s lifecycle: reverse transcriptase, integrase and protease. Historically, most people ...

Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase (RT ... prolonged treatment with multiple nucleoside RT inhibitors. The occurrence of reading frame shifts ...

Cosalane is undergoing preclinical development. Also has developed a new reverse transcriptase inhibitor called "ADAM," and analogs of it are being created and evaluated as HIV-1 reverse transcriptase ...

More than 46,000 of them had been prescribed a form of HIV-suppressing medications known as reverse transcriptase (RT) inhibitors. Among this subgroup, Alzheimer's diagnoses occurred in about 2.5 ...

To test whether targeting transposable elements could help treat cancer, Gudkov, Greenbaum, and others have examined the effect of giving cancer cells a so-called reverse transcriptase inhibitor that ...

This fixed-dose tablet combines 600mg efavirenz, 200mg emtricitabine (FTC), and 245mg tenofovir disoproxil fumarate (TDF). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI), ...

Nevirapine (as hemihydrate) 50mg/5mL. Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. Nevirapine binds directly to reverse transcriptase (RT) and blocks the RNA ...