shotgun proteomics identifies proteins from tandem mass spectra of their proteolytic peptides 5. To explain by analogy, imagine you find a box of old-fashioned geared watches in an antique store ...

Peptide-centric approaches—sometimes referred to as shotgun strategies or bottom-up proteomics—are now widely adopted as a means of identifying proteins present in biological mixtures.

The timsTOF Pro uses the Parallel Accumulation Serial Fragmentation (PASEF) acquisition method to provide extremely high speed and sensitivity to reach new depths in shotgun proteomics and ...

Saraf is the director of the Mass Spectrometry & Analytical Proteomics Laboratory at the University of Kansas, where she uses shotgun proteomics to analyze biological samples -; basic science that ...

Proteomics has significantly improved our understanding ... proteins and the solubilizing of hydrophobic proteins. A shotgun ...