Zocor (simvastatin) and Lipitor (atorvastatin) are both statin drugs, which are medications used to lower cholesterol levels in the blood. Statins primarily work by inhibiting the enzyme HMG-CoA ...

The mean (± SD) relative decreases of LDL-C from baseline were: 14.0 ± 14.1% for atorvastatin 20mg (n = 107) versus 3.3 ± 14.1% for simvastatin 20mg (n = 108) [p = 0.0001], and 14.7 ± 15.2% ...

Atorvastatin use is also related to a higher frequency of abnormally high UAE when compared with those patients taking simvastatin as a lipid-lowering drug. No differences were observed in lipid ...

Statins, including atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, simvastatin and rosuvastatin, are therefore widely used for both primary and secondary prevention of ASCVD.