(A single colony arises from one cell going ... Singh, R. K. & Krishna, M. DNA strand breaks signal the induction of DNA double-strand break repair in Saccharomyces cerevisiae.

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

Single-strand breaks generated during DNA repair were observed converting to double-strand breaks and reversibly switching between states in response to oxidation in cultured neurons as well as in ...

These mechanisms can detect and correct different types of DNA damage, such as base mismatches, single-strand breaks, and double-strand breaks. DNA repair is essential for preventing the accumulation ...

Efficient DNA repair mechanisms have evolved to ensure ... polymerase η; SSB, single-strand break; TCR, transcription-coupled repair. Abbreviations: BER, base excision repair; DSB, double-stand ...

RecA is a bacterial protein that is crucial for repairing double-stranded breaks in DNA via the process of homologous recombination. RecA binds to single-stranded DNA, searches along a separate piece ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

DNA ligases IIIa (922 amino acids) and IIIb (862 amino acids) are the products of a single gene; they differ in amino acid sequence only at their ... DNA ligase IV is a 911-amino acid polypeptide that ...

Base and Prime Editing Offer Precision CRISPR-based systems that rely on traditional Cas nucleases like Cas9 cut through both strands of DNA which can lead to undesirable and even dangerous edits to ...