2021 年,一篇题为“Small RNAs are modified with N - glycans and displayed on the surface of living cells”的论文在 Cell ...
A study published in PNAS reveals how a bacterial pathogen coordinates N-acetylneuraminic acid (Neu5Ac) metabolism at the ...
UMI Small RNA测序,文库构建时引入特异性分子标签(UMI),结合高通量测序,研究某物种某组织在特定时空状态下18-30 nt的small RNA片段序列信息,实现绝对定量,通过与数据库比对, 可实现small RNA序列的鉴定、预测、靶基因分析和功能分析, 以及包含miRNA、siRNA ...
Figure 2: DGE profiling analysis of a synthetic RNA pool. To determine whether DGE profiling allows for differential expression analysis, we sequenced small RNA libraries from rat spleen and liver ...
One application in which the technology has had a considerable impact is small RNA analysis. Figure 3: Before emPCR and sequencing, Genome Sequencer process–specific A and B adaptors must be ...
"RNA interference is a well-known type of gene regulation in which cells can turn down the expression of a gene by expressing a small RNA that can base pair with the RNA of the target gene.
Using $1.8 million in federal funding, a biologist at The University of Texas at Arlington is heading up a project that could ...
Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.