来自MSN2 天
100-year-old heart drug made from foxglove may help 'dissolve' clumps of spreading cancer cells
The heart drug digoxin could potentially be combined with existing cancer therapies to prevent the spread of tumors, an early ...
Nature9 天
Altered fluid, electrolyte and mineral status in tropical disease, with an emphasis on ...
Large amounts of sodium and potassium are lost in stool as a result ... and occasionally from decreased activity of Na +,K +-ATPase. Hypocalcemia, hypomagnesemia and hypophosphatemia are common ...
Nature1 个月
Ion channels: From idea to reality
Figure 1: My 1967 thesis drawing of an excitable membrane showing three separate types of ion channels Na, K and leak (L), as well as the Na-K ATPase ... pores of sodium and potassium channels ...
Healio2 年
Digoxin Toxicity Topic Review
Digoxin blocks the sodium/potassium ATPase pump. The mechanism by which this decreases AV conduction is not clear but is perhaps due to increased vagal tone. Intracellular calcium within the ...