Asynt report that the Cresswell Group, led by Dr Alexander J. Cresswell at the University of Bath (UK), have demonstrated the synthesis of novel spirocyclic tetrahydonaphthyridines (THNs) expanding ...

After many trials, Zhou’s team found that spirocyclic molecules, with a spiral structure, allowed the highest selectivity and activity for reactions. By modifying these molecules, they designed ...

Cresswell at the University of Bath (UK), have demonstrated the synthesis of novel spirocyclic tetrahydonaphthyridines (THNs) expanding the chemical space of these important scaffolds for drug ...