However, they might recommend starting with 25 mg a day and slowly increasing your dose to reduce your risk of side effects. Spironolactone sometimes causes drowsiness, so it’s best to take it ...

Spironolactone was initiated at a dose of 25 mg daily at the first ambulatory blood ... Spironolactone inhibits the effects of aldosterone by binding to the mineralocorticoid receptor.

The drug can sometimes ... that physicians prescribe spironolactone more freely in practice. Juurlink et al. have carried out a time-series analysis to examine the effects of RALES at the ...