Figure 2: Going inside the spines and exploring synaptic proteins that support the function of individual synapses. Thus, the truth may be a mixture of these two possibilities, to say the least ...
What other signaling molecules function along with neurexin and neuroligin in synapse formation, and how are the molecular interactions orchestrated? The present picture of the neurexin ...
An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...
The Johns Hopkins team found that, even without the enzymatic activity, the synapse worked normally, suggesting that the structural property alone is very important for SynGAP function.
The ultimate effect of a signal from one neuron on the next neuron depends on the function of the synapse, which is based on the type of neurotransmitter released. Excitatory synapses send signals ...
Following development, synapses continue to remodel throughout life, which is important for processes like learning and memory. Given their importance in brain function, it is not surprising that ...
New research reveals how electrical synapses filter sensory input, helping animals choose actions based on context.
Scientists in Japan say they have reversed the signs of Alzheimer’s disease in lab mice by restoring the healthy function of synapses, critical parts of neurons that shoot chemical messages to ...
“It would be interesting to investigate whether improving endolysosomal function, as we did in aged neurons, recovers synapses,” she wrote. Almeida found that restoring the acid pH of lysosomes ...