in which discrepancies were observed between chemical and biological methods of penicillin assay when a precursor was omitted from penicillin fermentations.

An efficient total-synthesis pathway with extraordinary flexibility ... against bacteria known to be resistant to tetracycline, penicillin, methicillin and/or vancomycin. These derivatives were ...

One famous example is penicillin, which was unintentionally ... drugs has relied heavily on the identification, isolation, and synthesis of novel bioactive chemicals from bacteria, fungi, and ...