Researchers provided a long-awaited and rare genetic diagnosis in a child with Lennox-Gastaut syndrome, a type of ...

For example, because X chromosome inactivation is not completely effective, some genes that escape silencing may still express at low levels, and their protein products may interact with Xist. With ...

Patients with Klinefelter and triple X syndromes show an increased prevalence of SLE and Sjögren disease, likely due to the synergistic interaction of the extra X chromosomes.

Female mammals typically carry two X chromosomes — one from each parent ... so they could look at which genes were switched on. Three genes were silenced on the maternal X — Sash3, Tlr7 ...

Lee and her colleagues have theorized that in cases where genetic disorders are the result of a mutation on the X chromosome, the inactivated X chromosome could serve as a "backup copy," and that ...