Two fundamental mechanisms of gene regulation involve transcription factors and microRNAs, a large class of small, non-coding RNAs. It is widely believed that phenotypic evolution is closely ...

Transcription factors (TFs) are key cellular components that control gene expression. Their activity determines how cells function and respond to cellular environments. Despite intense scientific ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...

在国家自然科学基金项目（批准号：81930030、82230036）等资助下，浙江大学马欢教授团队在大脑动态“充电供能”的神经可塑性机制研究方面取得进展。研究成果以“促进神经活动-线粒体DNA转录偶联改善老年小鼠认知（Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in ...

“R-loops are generally bad news, so cells have many redundant mechanisms to prevent them from forming,” says Seth Darst, head ...

"Each gene was like a single word. However, there was a piece of critical information lacking: transcription initiation sites for individual genes." Transcription initiation sites are locations in ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled ...

JERUSALEM - Israeli scientists have discovered a unique genetic mechanism that provides human cells with efficient protection ...