“This is the first time there is a relatively easy path to synthesize macrolide erythromycin-type antibiotics from scratch.” For most of the field’s history, natural products have been the starting ...

This increase has raised concerns about antibiotic resistance, particularly to macrolides, which are commonly used to treat various bacterial infections. Recent research has focused on ...

Among adults treated for community-acquired pneumonia in the outpatient setting, broad-spectrum antibiotics vs macrolide monotherapy were associated with an increased risk for adverse drug events.

Macrolide maintenance therapy in patients with bronchiectasis significantly reduces the risk for major adverse cardiovascular events.

This increase in resistance has paralleled a similar rise in macrolide resistance in other respiratory pathogens apparently as a result of antibiotic selective pressure in children during a period ...