This article reviews multiple aspects of infiltration and extravasation injury. First, starting at the cellular level the role of vesicants in vascular injury and its role triggering inflammation ...

The measurement of the concentration of hydrogen ions, pH, is another important consideration when evaluating a medication's risk of infiltration or extravasation. A normal pH of blood is between ...

Dacarbazine is a potent vesicant (it is corrosive), and it should be carefully administered to avoid the risk of extravasation ... is a chemotherapy medication used to treat cancer.