The epithelial lining of our intestine is organized in a crypt-villi architecture and serves many essential functions including maintenance of barrier, digestion and nutrient absorption. Due to the ...
Theoretically, for drugs that easily penetrate the intestinal mucosa, reduced villus blood flow could delay diffusion and, therefore, the rate of absorption. For example, the absorption rate for ...
Intestinal villi, with their branching projections and folds, increase the surface area for absorption tremendously. With a combination of the villi and microvilli in the small intestine ...