The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...

The biology of RNA interference has greatly facilitated analysis of loss-of-function phenotypes, but correlating these phenotypes with small-molecule inhibition profiles is not always straightforward.

The most recent addition to the methods hall of fame is RNA interference (RNAi). The discovery of a whole universe of small RNAs with regulatory functions of fundamental importance was entirely ...

2月13日，RNAi（RNA干扰）疗法领域的领军企业 Alnylam Pharmaceuticals (纳斯达克代码：ALNY) ...

虽然这些产品在RNAi技术的害虫控制方面代表了重大进步，但在开发方面仍有很长的路要走，特别是对于外源应用。然而，观察到对这些应用的开发越来越重视（图4）。然而，大多数研究的基础研究水平在中到低范围，表明需要进一步优化以推进产品开发的市场成熟。

Her writing focuses on gene editing technology, cell and gene therapies, and the regulatory space. View Full Profile. Learn about our Editorial Policies. The natural RNAi mechanism can be directed by ...

Scientists seek innovative approaches to address this health crisis, some of which are therapeutics poised to treat CVD in new ways. RNA interference (RNAi) therapeutics silence genes, disrupting the ...

RNA, or ribonucleic acid, is a essential biological molecule that plays a crucial role in various cellular processes. It is a polymeric molecule composed of nucleotides, each containing a ribose sugar ...

For discussion questions and lesson plans, go to the RNA Lab collection on PBS LearningMedia. The standards-based NOVA RNA Lab allows users to explore the science of RNA and learn how to design ...