The crystal structure of pseudouridine synthase I from Escherichia coli, which, for example, modifies positions 38, 39 and/or 40 in tRNA, reveals a dimeric protein that contains two positively ...

A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...

There is much more to the story, however, particularly with regard to chromosomal structure and organization. Supercoiling explains how chromosomes fit into a small corner of the cell, but how do ...

“E. coli is a bug that we all have in our intestines,” explains Britain's leading expert on E. coli, the microbiologist Professor Hugh Pennington. “The vast majority of the hundreds of different ...