Most organic drugs contain one acid group, usually a carboxylic acid, -COOH, or one basic primary, secondary, or tertiary amino group, NC 1-3, [3,22,27,28,29] that determines the acid-base ...
For example, for the Source 1 dilution, the concentration = {([2 mL × 47.6 mg/mL]/50 mL) × [1000 µg/mg] × [3.07/100]} = 58.45 µg/mL. i The soluble concentration of nonionized phenytoin might ...