Cohesin plays a crucial role in both chromosome organization and DNA repair. Here the authors find that cohesin mediated genome architecture prevents interactions between damaged chromatin.

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Alkylating agents cause breakage of DNA strand to help thwart the ability ... 5 at 9:05 a.m. ET Novartis' Kisqali has secured a label expansion from the U.K.'s Medicines and Healthcare products ...

Psoralen-conjugated triplex-forming oligonucleotides (Ps-TFOs) have been employed for the photodynamic regulation of gene expression by the photo-cross-linking of psoralen with the target DNA ...

Targeting the lowest performers may be logical for the companies' bottom lines, but the publicity surrounding layoffs can give those a negative label that can compound the difficulties of being ...

Anheuser-Busch is encouraging its distributors and partners to replace the term “domestic” with “American” when marketing beer, arguing that the term better reflects the industry’s identity.