The recommended dosage of alvimopan is 12 mg administered with a sip of water 30 minutes to five hours before surgery, followed by 12 mg twice daily beginning the day after surgery for a maximum ...

2009;66(14):1267-1277. The second study group (n = 26) received placebo or increasing alvimopan doses (0.5, 1.5, 3, or 4.5 mg on days 1–4, respectively). Stool weight increased daily through day ...