Antimicrobial peptides (AMPs) are promising novel antibiotics since they have ... The next step is the hydrophobic interactions between the amphipathic domains of the peptide and the membrane ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

Here, we review the extensively studied targets, i.e., MurA, MurB, MurC, MurD, MurE, MurF, Alr, Ddl, MurI, MurG, lipid A, and BamA in the cell wall, starting from the very beginning to the latest ...

A groundbreaking cannabinoid-based antimicrobial, Silvanex, fights drug-resistant infections with a synergy of silver, CBC ...

Tuberculosis is a serious global health threat that infected more than 10 million people in 2022. Spread through the air and ...

The search for new tuberculosis drug targets under traditional laboratory methods has historically proven to be arduous and ...

Real-time imaging shows that bacterial resilience to antibiotics is not caused by a few ‘persisters’, but is a ...

Antibiotics are indispensable for treating bacterial infections. But why are they sometimes ineffective, even when the ...

Antibiotics are indispensable for treating bacterial infections. But why are they sometimes ineffective, even when the bacteria are not resistant? In their latest study published in the journal Nature ...

Diet plays a pivotal role in influencing autoimmune diseases like multiple sclerosis (MS), inflammatory bowel disease, and ...

The data suggests that the body's use of nutrient scarcity as a defense mechanism may actually enable bacteria's survival in the long run.

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...