Major strengths: • Demonstration of CCR4 deficiency's impact on early atherosclerosis. CCR4 deficiency effects on the early atherosclerosis development in the Apoe-/-mice model were demonstrated by a ...

Although C-C chemokine receptor 4 (CCR4) has been shown to mediate the recruitment of T cells to inflamed tissues, its role in atherosclerosis is unclear. Here, we show that genetic deletion of CCR4 ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...

Real-time observation of certain biochemical processes in blood vessels from mice has revealed a previously unknown similarity between atherosclerosis, also known as vascular calcification ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment ...

Binary logistic regression model was done to obtain the odds ratios (ORs) and 95% confidence intervals (95% CI) for the risk of the presence of carotid atherosclerosis based on Metrnl quartile.

We appreciated the FDA reviewers' alignment with our proposed clinical development program, and their positive feedback on our intended clinical trial design, IND-enabling studies, and drug ...

The Glorious Model O 2 Mini Wireless is a fantastic gaming mouse that slims its package down into a super versatile pointer for smaller hands. Everything runs smoothly and with excellent snap to ...

IRX4204, a compound that Io Therapeutics is developing to treat neurological diseases, facilitated myelin repair and improved walking abilities in a mouse model of multiple sclerosis (MS ...

Using the best mouse can have a transformative effect on your overall PC experience. More than just a peripheral device, a decent mouse controls the ebb and flow of your workflow management ...