We are interested in mechanisms that regulate RNA Stress Granule (SG) and Processing Body (P-body) formation in cells. These two types of RNA granules aggregate translationally-silenced mRNAs and ...

Recent work has shown us that G3BP nucleation of stress granules in the absence of virus infection activates PKR, resulting in phosphorylation of eIF2alpha and activation of NF-kB and JNK signal ...

With the new aerobic granular sludge technology (Nereda TM), aerobic (thus oxygen using) bacterial granules are formed in the water that is to be purified. The great advantage of these granules is ...

However, as a bacterial colony develops, “growing pains” are inevitable, as proliferating cells must balance growth rates with the stress of overcrowding and nutrient resource limitations. Other ...

The researchers found that the ZO-1 protein directs YB-1 to form beneficial stress granules. Stress granules are clusters of proteins that assemble inside cells exposed to stressful conditions ...

By connecting these devices to a syringe and pump, they generate realistic flow environments to study how bacteria respond under stress. Previous research from Sanfilippo's lab uncovered the ...