This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

The most common neonatal presentation of Candida infections is invasive bloodstream infection and may be viewed as primary or secondary to other sites of primary infection. Infection can originate ...

Department of Chemistry, Graduate School of Science, Tohoku University, 6-3 Aramaki-Aza Aoba, Aoba-ku, Sendai 980-8578, Japan JST, PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan JST, FOREST, ...

THE use of the complement-fixation test in serologic investigation serves as a frequent reminder to the physician of the existence of the complement system. It is probable that despite the ...

The complement system is tightly regulated by factors such as FH, C1INH, MASP-1, MASP-2, C3, C5, and the C5a-C5aR1 and C3a-C3aR1 complexes, which collectively shape immune responses and inflammation.

Additionally, the complement C5a-C5aR pathway has been identified as a crucial factor in gastric cancer development. The impact of the complement system on iron metabolism and its role in gastric ...

Marked conformational rearrangements of C3 and factor B are central to their biological functions. The structure of complement protein C3 reveals a large, modular protein consisting of 13 domains ...

The complement system has more than 50 soluble and membrane-bound proteins. In innate and adaptive immunity, complement is essential for eliminating foreign pathogens and apoptotic cells.

As we start the new year, the state must realise that the young people of Pakistan deserve better; that it must listen and consider their needs. Updated 06 Jan, 2025 03:26pm ...