However, the requirement of PPAR-γ for monocytic differentiation and the relative contribution of the PPAR-γ–CD36 pathway to lipid uptake in differentiated macrophages have not been tested.

3Department of Pathology, Yale School of Medicine, New Haven, Connecticut. 4Department of Dermatology, Yale School of Medicine, New Haven, Connecticut. 5Yale Center for Precision Cancer Modeling, Yale ...

In this narrative and critical review, we aim to see the potential use of immune cells modulation or cell therapy as therapeutic alternatives to OA patients. Macrophages are immune cells that are ...

Liver kinase B1 (LKB1) is known to shape the regulation of macrophage function by participating in multiple processes including cell metabolism, growth, and polarization. However, whether LKB1 also ...

Burke Neurological Institute, White Plains, NY (H.J., I.P., K.W.P., J.M., A.M., S.C.). InVitro Cell Research, Englewood, NJ (H.J., J.W.C.). Helen & Robert Appel ...

2 Its specificity for RA is thus limited. Here we describe the mRNA and protein expression of PAD enzymes in monocytes and macrophages, as well as in synovial fluid mononuclear cells (SFMCs). Possible ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...

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Xiamen Cell Therapy Research Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361003, China ...